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Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

학술저널

issue: Nature Communications. 14(1)
Author: de Rojas, Itziar^{Aff1, Aff2}
Moreno-Grau, Sonia^{Aff1, Aff2}
Tesi, Niccolo^{Aff3, Aff4, Aff5}
Grenier-Boley, Benjamin
Andrade, Victor^{Aff7, Aff8}
Jansen, Iris E.^{Aff3, Aff9}
Pedersen, Nancy L.
Stringa, Najada
Zettergren, Anna
Hernández, Isabel^{Aff1, Aff2}
Montrreal, Laura
Antúnez, Carmen
Antonell, Anna
Tankard, Rick M.
Bis, Joshua C.
Sims, Rebecca
Bellenguez, Céline
Quintela, Inés
González-Perez, Antonio
Calero, Miguel^{Aff2, Aff20, Aff21}
Franco-Macías, Emilio
Macías, Juan
Blesa, Rafael^{Aff2, Aff24}
Cervera-Carles, Laura^{Aff2, Aff24}
Menéndez-González, Manuel^{Aff25, Aff26, Aff27}
Frank-García, Ana^{Aff2, Aff28, Aff29, Aff30}
Royo, Jose Luís
Moreno, Fermin^{Aff2, Aff32, Aff33}
Huerto Vilas, Raquel^{Aff34, Aff35}
Baquero, Miquel
Diez-Fairen, Mónica^{Aff37, Aff38}
Lage, Carmen^{Aff2, Aff39}
García-Madrona, Sebastián
García-González, Pablo
Alarcón-Martín, Emilio^{Aff1, Aff31}
Valero, Sergi^{Aff1, Aff2}
Sotolongo-Grau, Oscar
Ullgren, Abbe^{Aff41, Aff42}
Naj, Adam C.^{Aff43, Aff44}
Lemstra, Afina W.
Benaque, Alba
Pérez-Cordón, Alba
Benussi, Alberto
Rábano, Alberto^{Aff2, Aff21, Aff46}
Padovani, Alessandro
Squassina, Alessio
de Mendonça, Alexandre
Arias Pastor, Alfonso^{Aff34, Aff35}
Kok, Almar A. L.^{Aff11, Aff49}
Meggy, Alun
Pastor, Ana Belén^{Aff21, Aff46}
Espinosa, Ana^{Aff1, Aff2}
Corma-Gómez, Anaïs
Martín Montes, Angel^{Aff2, Aff29, Aff51}
Sanabria, Ángela^{Aff1, Aff2}
DeStefano, Anita L.^{Aff52, Aff53}
Schneider, Anja^{Aff8, Aff54}
Haapasalo, Annakaisa
Kinhult Ståhlbom, Anne^{Aff41, Aff42}
Tybjærg-Hansen, Anne^{Aff56, Aff57}
Hartmann, Annette M.
Spottke, Annika^{Aff54, Aff59}
Corbatón-Anchuelo, Arturo^{Aff60, Aff61}
Rongve, Arvid^{Aff62, Aff63}
Borroni, Barbara
Arosio, Beatrice^{Aff64, Aff65}
Nacmias, Benedetta^{Aff66, Aff67}
Nordestgaard, Børge G.^{Aff57, Aff68}
Kunkle, Brian W.^{Aff69, Aff70}
Charbonnier, Camille
Abdelnour, Carla^{Aff1, Aff2}
Masullo, Carlo
Martínez Rodríguez, Carmen^{Aff26, Aff73}
Muñoz-Fernandez, Carmen
Dufouil, Carole^{Aff75, Aff76}
Graff, Caroline^{Aff41, Aff42}
Ferreira, Catarina B.
Chillotti, Caterina
Reynolds, Chandra A.
Fenoglio, Chiara
Van Broeckhoven, Christine^{Aff81, Aff82, Aff83}
Clark, Christopher
Pisanu, Claudia
Satizabal, Claudia L.^{Aff52, Aff85, Aff86}
Holmes, Clive
Buiza-Rueda, Dolores^{Aff2, Aff88}
Aarsland, Dag^{Aff89, Aff90}
Rujescu, Dan
Alcolea, Daniel^{Aff2, Aff24}
Galimberti, Daniela^{Aff80, Aff91}
Wallon, David
Seripa, Davide
Grünblatt, Edna^{Aff94, Aff95, Aff96}
Dardiotis, Efthimios
Düzel, Emrah^{Aff98, Aff99}
Scarpini, Elio^{Aff80, Aff91}
Conti, Elisa
Rubino, Elisa
Gelpi, Ellen^{Aff102, Aff103}
Rodriguez-Rodriguez, Eloy^{Aff2, Aff39}
Duron, Emmanuelle^{Aff104, Aff105, Aff106}
Boerwinkle, Eric^{Aff107, Aff108}
Ferri, Evelyn
Tagliavini, Fabrizio
Küçükali, Fahri^{Aff81, Aff82, Aff83}
Pasquier, Florence^{Aff110, Aff111}
Sanchez-Garcia, Florentino
Mangialasche, Francesca
Jessen, Frank^{Aff54, Aff114, Aff115}
Nicolas, Gaël
Selbæk, Geir^{Aff116, Aff117, Aff118}
Ortega, Gemma^{Aff1, Aff2}
Chêne, Geneviève^{Aff75, Aff76}
Hadjigeorgiou, Georgios
Rossi, Giacomina
Spalletta, Gianfranco^{Aff120, Aff121}
Giaccone, Giorgio
Grande, Giulia
Binetti, Giuliano^{Aff123, Aff124}
Papenberg, Goran
Hampel, Harald
Bailly, Henri^{Aff106, Aff126}
Zetterberg, Henrik^{Aff127, Aff128, Aff129, Aff130}
Soininen, Hilkka^{Aff131, Aff132}
Karlsson, Ida K.^{Aff10, Aff133}
Alvarez, Ignacio^{Aff37, Aff38}
Appollonio, Ildebrando^{Aff100, Aff134}
Giegling, Ina
Skoog, Ingmar
Saltvedt, Ingvild^{Aff135, Aff136}
Rainero, Innocenzo
Rosas Allende, Irene^{Aff26, Aff138}
Hort, Jakub^{Aff139, Aff140}
Diehl-Schmid, Janine
Van Dongen, Jasper^{Aff81, Aff82}
Vidal, Jean-Sebastien^{Aff106, Aff126}
Lehtisalo, Jenni^{Aff131, Aff142}
Wiltfang, Jens^{Aff143, Aff144, Aff145}
Thomassen, Jesper Qvist
Kornhuber, Johannes
Haines, Jonathan L.^{Aff147, Aff148}
Vogelgsang, Jonathan^{Aff143, Aff149}
Pineda, Juan A.
Fortea, Juan^{Aff2, Aff24}
Popp, Julius^{Aff150, Aff151, Aff152}
Deckert, Jürgen
Buerger, Katharina^{Aff154, Aff155}
Morgan, Kevin
Fließbach, Klaus
Sleegers, Kristel^{Aff81, Aff82, Aff83}
Molina-Porcel, Laura^{Aff14, Aff102}
Kilander, Lena
Weinhold, Leonie
Farrer, Lindsay A.
Wang, Li-San
Kleineidam, Luca^{Aff7, Aff8}
Farotti, Lucia
Parnetti, Lucilla
Tremolizzo, Lucio^{Aff100, Aff134}
Hausner, Lucrezia
Benussi, Luisa
Froelich, Lutz
Ikram, M. Arfan
Deniz-Naranjo, M. Candida
Tsolaki, Magda
Rosende-Roca, Maitée^{Aff1, Aff2}
Löwenmark, Malin
Hulsman, Marc^{Aff3, Aff4}
Spallazzi, Marco
Pericak-Vance, Margaret A.
Esiri, Margaret
Bernal Sánchez-Arjona, María
Dalmasso, Maria Carolina
Martínez-Larrad, María Teresa^{Aff60, Aff61}
Arcaro, Marina
Nöthen, Markus M.
Fernández-Fuertes, Marta
Dichgans, Martin^{Aff154, Aff155, Aff167}
Ingelsson, Martin
Herrmann, Martin J.
Scherer, Martin
Vyhnalek, Martin^{Aff139, Aff140}
Kosmidis, Mary H.
Yannakoulia, Mary
Schmid, Matthias^{Aff54, Aff158}
Ewers, Michael^{Aff154, Aff155}
Heneka, Michael T.^{Aff8, Aff54}
Wagner, Michael^{Aff8, Aff54}
Scamosci, Michela
Kivipelto, Miia^{Aff113, Aff172, Aff173, Aff174}
Hiltunen, Mikko
Zulaica, Miren^{Aff2, Aff33}
Alegret, Montserrat^{Aff1, Aff2}
Fornage, Myriam
Roberto, Natalia
van Schoor, Natasja M.
Seidu, Nazib M.
Banaj, Nerisa
Armstrong, Nicola J.
Scarmeas, Nikolaos^{Aff177, Aff178}
Scherbaum, Norbert
Goldhardt, Oliver
Hanon, Oliver^{Aff106, Aff126}
Peters, Oliver^{Aff180, Aff181}
Skrobot, Olivia Anna
Quenez, Olivier
Lerch, Ondrej^{Aff139, Aff140}
Bossù, Paola
Caffarra, Paolo
Dionigi Rossi, Paolo
Sakka, Paraskevi
Mecocci, Patrizia
Hoffmann, Per^{Aff166, Aff186}
Holmans, Peter A.
Fischer, Peter
Riederer, Peter
Yang, Qiong
Marshall, Rachel
Kalaria, Rajesh N.^{Aff189, Aff190}
Mayeux, Richard^{Aff191, Aff192, Aff193}
Vandenberghe, Rik^{Aff194, Aff195}
Cecchetti, Roberta
Ghidoni, Roberta
Frikke-Schmidt, Ruth^{Aff56, Aff57}
Sorbi, Sandro^{Aff66, Aff67}
Hägg, Sara
Engelborghs, Sebastiaan^{Aff196, Aff197, Aff198, Aff199}
Helisalmi, Seppo
Botne Sando, Sigrid^{Aff201, Aff202}
Kern, Silke
Archetti, Silvana
Boschi, Silvia
Fostinelli, Silvia
Gil, Silvia
Mendoza, Silvia
Mead, Simon
Ciccone, Simona
Djurovic, Srdjan^{Aff206, Aff207}
Heilmann-Heimbach, Stefanie
Riedel-Heller, Steffi
Kuulasmaa, Teemu
del Ser, Teodoro
Lebouvier, Thibaud^{Aff110, Aff111}
Polak, Thomas
Ngandu, Tiia^{Aff113, Aff142}
Grimmer, Timo
Bessi, Valentina^{Aff66, Aff210}
Escott-Price, Valentina^{Aff17, Aff211}
Giedraitis, Vilmantas
Deramecourt, Vincent^{Aff110, Aff111}
Maier, Wolfgang^{Aff8, Aff54}
Jian, Xueqiu
Pijnenburg, Yolande A. L.
Kehoe, Patrick Gavin
Garcia-Ribas, Guillermo
Sánchez-Juan, Pascual^{Aff2, Aff39}
Pastor, Pau^{Aff37, Aff38}
Pérez-Tur, Jordi^{Aff2, Aff212, Aff213}
Piñol-Ripoll, Gerard^{Aff34, Aff35}
Lopez de Munain, Adolfo^{Aff2, Aff32, Aff33, Aff214}
García-Alberca, Jose María^{Aff2, Aff204}
Bullido, María J.^{Aff2, Aff30, Aff215, Aff216}
Álvarez, Victoria^{Aff26, Aff138}
Lleó, Alberto^{Aff2, Aff24}
Real, Luis M.^{Aff23, Aff217}
Mir, Pablo^{Aff2, Aff88}
Medina, Miguel^{Aff2, Aff21}
Scheltens, Philip
Holstege, Henne^{Aff3, Aff4}
Marquié, Marta^{Aff1, Aff2}
Sáez, María Eugenia
Carracedo, Ángel^{Aff18, Aff218}
Amouyel, Philippe
Schellenberg, Gerard D.
Williams, Julie^{Aff17, Aff50}
Seshadri, Sudha^{Aff52, Aff85, Aff219}
van Duijn, Cornelia M.^{Aff162, Aff220}
Mather, Karen A.^{Aff221, Aff222}
Sánchez-Valle, Raquel
Serrano-Ríos, Manuel^{Aff60, Aff61}
Orellana, Adelina^{Aff1, Aff2}
Tárraga, Lluís^{Aff1, Aff2}
Blennow, Kaj^{Aff127, Aff128}
Huisman, Martijn^{Aff11, Aff223}
Andreassen, Ole A.^{Aff224, Aff225}
Posthuma, Danielle
Clarimón, Jordi^{Aff2, Aff24}
Boada, Mercè^{Aff1, Aff2}
van der Flier, Wiesje M.
Ramirez, Alfredo^{Aff7, Aff8, Aff54, Aff226}
Lambert, Jean-Charles
van der Lee, Sven J.^{Aff3, Aff4, IDs4146702336192x_cor297}
Ruiz, Agustín^{Aff1, Aff2, IDs4146702336192x_cor298}
DB Label: Database : Springer Nature Journals

원문보기: OA (Nature) OA (Springer) 조회 - Impact Factor (JCR) 등재 - Web of Science (SCIE) 등재 - SCOPUS

New insights into the genetic etiology of Alzheimer’s disease and related dementias

학술저널

issue: Nature Genetics. 54(4)
Author: Bellenguez, Céline
Küçükali, Fahri
Jansen, Iris E
Kleineidam, Luca
Moreno-Grau, Sonia
Amin, Najaf
Naj, Adam C
Campos-Martin, Rafael
Grenier-Boley, Benjamin
Andrade, Victor
Holmans, Peter A
Boland, Anne
Damotte, Vincent
van der Lee, Sven J
Costa, Marcos R
Kuulasmaa, Teemu
Yang, Qiong
de Rojas, Itziar
Bis, Joshua C
Yaqub, Amber
Prokic, Ivana
Chapuis, Julien
Ahmad, Shahzad
Giedraitis, Vilmantas
Aarsland, Dag
Garcia-Gonzalez, Pablo
Abdelnour, Carla
Alarcón-Martín, Emilio
Alcolea, Daniel
Alegret, Montserrat
Alvarez, Ignacio
Álvarez, Victoria
Armstrong, Nicola J
Tsolaki, Anthoula
Antúnez, Carmen
Appollonio, Ildebrando
Arcaro, Marina
Archetti, Silvana
Pastor, Alfonso Arias
Arosio, Beatrice
Athanasiu, Lavinia
Bailly, Henri
Banaj, Nerisa
Baquero, Miquel
Barral, Sandra
Beiser, Alexa
Pastor, Ana Belén
Below, Jennifer E
Benchek, Penelope
Benussi, Luisa
Berr, Claudine
Besse, Céline
Bessi, Valentina
Binetti, Giuliano
Bizarro, Alessandra
Blesa, Rafael
Boada, Mercè
Boerwinkle, Eric
Borroni, Barbara
Boschi, Silvia
Bossù, Paola
Bråthen, Geir
Bressler, Jan
Bresner, Catherine
Brodaty, Henry
Brookes, Keeley J
Brusco, Luis Ignacio
Buiza-Rueda, Dolores
Bûrger, Katharina
Burholt, Vanessa
Bush, William S
Calero, Miguel
Cantwell, Laura B
Chene, Geneviève
Chung, Jaeyoon
Cuccaro, Michael L
Carracedo, Ángel
Cecchetti, Roberta
Cervera-Carles, Laura
Charbonnier, Camille
Chen, Hung-Hsin
Chillotti, Caterina
Ciccone, Simona
Claassen, Jurgen AHR
Clark, Christopher
Conti, Elisa
Corma-Gómez, Anaïs
Costantini, Emanuele
Custodero, Carlo
Daian, Delphine
Dalmasso, Maria Carolina
Daniele, Antonio
Dardiotis, Efthimios
Dartigues, Jean-François
de Deyn, Peter Paul
de Paiva Lopes, Katia
de Witte, Lot D
Debette, Stéphanie
Deckert, Jürgen
del Ser, Teodoro
DB Label: Database : eScholarship

원문보기: Open Access (eScholarship)

Gene Expression Imputation Across Multiple Tissue Types Provides Insight Into the Genetic Architecture of Frontotemporal Dementia and Its Clinical Subtypes

학술저널

issue: Biological Psychiatry. 89(8)
Author: Reus, Lianne M
Pasaniuc, Bogdan
Posthuma, Danielle
Boltz, Toni
Consortium, International FTD-Genomics
Ferrari, Raffaele
Hernandez, Dena G
Nalls, Michael A
Rohrer, Jonathan D
Ramasamy, Adaikalavan
Kwok, John BJ
Dobson-Stone, Carol
Brooks, William S
Schofield, Peter R
Halliday, Glenda M
Hodges, John R
Piguet, Olivier
Bartley, Lauren
Thompson, Elizabeth
Hernández, Isabel
Ruiz, Agustín
Boada, Mercè
Borroni, Barbara
Padovani, Alessandro
Cruchaga, Carlos
Cairns, Nigel J
Benussi, Luisa
Binetti, Giuliano
Ghidoni, Roberta
Forloni, Gianluigi
Galimberti, Daniela
Fenoglio, Chiara
Serpente, Maria
Scarpini, Elio
Clarimón, Jordi
Lleó, Alberto
Blesa, Rafael
Waldö, Maria Landqvist
Nilsson, Karin
Nilsson, Christer
Mackenzie, Ian RA
Hsiung, Ging-Yuek R
Mann, David MA
Grafman, Jordan
Morris, Christopher M
Attems, Johannes
Griffiths, Timothy D
McKeith, Ian G
Thomas, Alan J
Pietrini, Pietro
Huey, Edward D
Wassermann, Eric M
Baborie, Atik
Jaros, Evelyn
Tierney, Michael C
Pastor, Pau
Razquin, Cristina
Ortega-Cubero, Sara
Alonso, Elena
Perneczky, Robert
Diehl-Schmid, Janine
Alexopoulos, Panagiotis
Kurz, Alexander
Rainero, Innocenzo
Rubino, Elisa
Pinessi, Lorenzo
Rogaeva, Ekaterina
St. George-Hyslop, Peter
Rossi, Giacomina
Tagliavini, Fabrizio
Giaccone, Giorgio
Rowe, James B
Schlachetzki, Johannes CM
Uphill, James
Collinge, John
Mead, Simon
Danek, Adrian
Van Deerlin, Vivianna M
Grossman, Murray
Trojanowski, John Q
van der Zee, Julie
Van Broeckhoven, Christine
Cappa, Stefano F
Le Ber, Isabelle
Hannequin, Didier
Golfier, Véronique
Vercelletto, Martine
Brice, Alexis
Nacmias, Benedetta
Sorbi, Sandro
Bagnoli, Silvia
Piaceri, Irene
Nielsen, Jørgen E
Hjermind, Lena E
Riemenschneider, Matthias
Mayhaus, Manuel
Ibach, Bernd
Gasparoni, Gilles
Pichler, Sabrina
Gu, Wei
DB Label: Database : eScholarship

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Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

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issue: Neuron. 109(3)
Author: Dewan, Ramita
Chia, Ruth
Ding, Jinhui
Hickman, Richard A
Stein, Thor D
Abramzon, Yevgeniya
Ahmed, Sarah
Sabir, Marya S
Portley, Makayla K
Tucci, Arianna
Ibáñez, Kristina
Shankaracharya, FNU
Keagle, Pamela
Rossi, Giacomina
Caroppo, Paola
Tagliavini, Fabrizio
Waldo, Maria L
Johansson, Per M
Nilsson, Christer F
Rowe, James B
Benussi, Luisa
Binetti, Giuliano
Ghidoni, Roberta
Jabbari, Edwin
Viollet, Coralie
Glass, Jonathan D
Singleton, Andrew B
Silani, Vincenzo
Ross, Owen A
Ryten, Mina
Torkamani, Ali
Tanaka, Toshiko
Ferrucci, Luigi
Resnick, Susan M
Pickering-Brown, Stuart
Brady, Christopher B
Kowal, Neil
Hardy, John A
Van Deerlin, Vivianna
Vonsattel, Jean Paul
Harms, Matt
Morris, Christopher M
Ferrari, Raffaele
Landers, John E
Chiò, Adriano
Gibbs, Jesse Raphael
Dalgard, Clifton L
Scholz, Sonja W
Traynor, Bryan J
Adeleye, Adelani
Alba, Camille
Bacikova, Dagmar
Hupalo, Daniel N
Martinez, Elisa McGrath
Pollard, Harvey B
Sukumar, Gauthaman
Soltis, Anthony R
Tuck, Meila
Zhang, Xijun
Wilkerson, Matthew D
Smith, Bradley N
Ticozzi, Nicola
Fallini, Claudia
Gkazi, Athina Soragia
Topp, Simon D
Kost, Jason
Scotter, Emma L
Kenna, Kevin P
Miller, Jack W
Tiloca, Cinzia
Vance, Caroline
Danielson, Eric W
Troakes, Claire
Colombrita, Claudia
Al-Sarraj, Safa
Lewis, Elizabeth A
King, Andrew
Calini, Daniela
Pensato, Viviana
Castellotti, Barbara
de Belleroche, Jacqueline
Baas, Frank
Asbroek, Anneloor LMA ten
Sapp, Peter C
McKenna-Yasek, Diane
McLaughlin, Russell L
Polak, Meraida
Asress, Seneshaw
Esteban-Pérez, Jesús
Muñoz-Blanco, José Luis
Stevic, Zorica
D’Alfonso, Sandra
Mazzini, Letizia
Comi, Giacomo P
Del Bo, Roberto
Ceroni, Mauro
Gagliardi, Stella
Querin, Giorgia
Bertolin, Cinzia
van Rheenen, Wouter
DB Label: Database : eScholarship

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C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts

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issue: Neurology. 95(24)
Author: Costa, Beatrice
Manzoni, Claudia
Bernal-Quiros, Manuel
Kia, Demis A
Aguilar, Miquel
Alvarez, Ignacio
Alvarez, Victoria
Andreassen, Ole
Anfossi, Maria
Bagnoli, Silvia
Benussi, Luisa
Bernardi, Livia
Binetti, Giuliano
Blackburn, Daniel
Boada, Mercè
Borroni, Barbara
Bowns, Lucy
Bråthen, Geir
Bruni, Amalia C
Chiang, Huei-Hsin
Clarimon, Jordi
Colville, Shuna
Conidi, Maria E
Cope, Tom E
Cruchaga, Carlos
Cupidi, Chiara
Di Battista, Maria Elena
Diehl-Schmid, Janine
Diez-Fairen, Monica
Dols-Icardo, Oriol
Durante, Elisabetta
Flisar, Dušan
Frangipane, Francesca
Galimberti, Daniela
Gallo, Maura
Gallucci, Maurizio
Ghidoni, Roberta
Graff, Caroline
Grafman, Jordan H
Grossman, Murray
Hardy, John
Hernández, Isabel
Holloway, Guy JT
Huey, Edward D
Illán-Gala, Ignacio
Karydas, Anna
Khoshnood, Behzad
Kramberger, Milica G
Kristiansen, Mark
Lewis, Patrick A
Lleó, Alberto
Madhan, Gaganjit K
Maletta, Raffaele
Maver, Aleš
Menendez-Gonzalez, Manuel
Milan, Graziella
Miller, Bruce
Mol, Merel O
Momeni, Parastoo
Moreno-Grau, Sonia
Morris, Chris M
Nacmias, Benedetta
Nilsson, Christer
Novelli, Valeria
Öijerstedt, Linn
Padovani, Alessandro
Pal, Suvankar
Panchbhaya, Yasmin
Pastor, Pau
Peterlin, Borut
Piaceri, Irene
Pickering-Brown, Stuart
Pijnenburg, Yolande AL
Puca, Annibale A
Rainero, Innocenzo
Rendina, Antonella
Richardson, Anna MT
Rogaeva, Ekaterina
Rogelj, Boris
Rollinson, Sara
Rossi, Giacomina
Rossmeier, Carola
Rowe, James B
Rubino, Elisa
Ruiz, Agustín
Sanchez-Valle, Raquel
Sando, Sigrid B
Santillo, Alexander F
Saxon, Jennifer
Scarpini, Elio
Serpente, Maria
Smirne, Nicoletta
Sorbi, Sandro
Suh, EunRan
Tagliavini, Fabrizio
Thompson, Jennifer C
Trojanowski, John Q
Van Deerlin, Vivianna M
Van der Zee, Julie
Van Broeckhoven, Christine
DB Label: Database : eScholarship

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A systematic review of progranulin concentrations in biofluids in over 7,000 people-assessing the pathogenicity of GRN mutations and other influencing factors

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