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Inhibition of B-cell lymphoma 2 family proteins alters optical redox ratio, mitochondrial polarization, and cell energetics independent of cell state.

학술저널

issue: Journal of biomedical optics [J Biomed Opt] 2022 May; Vol. 27 (5).
Author: Gillette AA; University of Wisconsin, Department of Biomedical Engineering, Madison, Wisconsin, United States.
DeStefanis RA; University of Wisconsin, McArdle Laboratory for Cancer Research, Department of Oncology, Madison, Wi, United States.
Pritzl SL; University of Wisconsin, Division of Hematology, Oncology and Palliative Care, Department of Medicin, United States.
Deming DA; University of Wisconsin, McArdle Laboratory for Cancer Research, Department of Oncology, Madison, Wi, United States.; University of Wisconsin, Division of Hematology, Oncology and Palliative Care, Department of Medicin, United States.; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin, United States.
Skala MC; University of Wisconsin, Department of Biomedical Engineering, Madison, Wisconsin, United States.; Morgridge Institute for Research, Madison, Wisconsin, United States.
DB Label: Database : MEDLINE

원문보기: Open Access (PubMed Central) 등재 - Web of Science (SCIE) 조회 - Impact Factor (JCR)

Impact of baseline culture conditions of cancer organoids when determining therapeutic response and tumor heterogeneity.

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issue: Scientific reports [Sci Rep] 2022 Mar 25; Vol. 12 (1), pp. 5205. Date of Electronic Publication: 2022 Mar 25.
Author: DeStefanis RA; Division of Hematology, Medical Oncology, and Palliative Care, Department of Medicine, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Ave, 6507 WIMR2, Madison, WI, 53705, USA.
Kratz JD; Division of Hematology, Medical Oncology, and Palliative Care, Department of Medicine, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Ave, 6507 WIMR2, Madison, WI, 53705, USA.; University of Wisconsin Carbone Cancer Center, Madison, WI, USA.
Olson AM; Division of Hematology, Medical Oncology, and Palliative Care, Department of Medicine, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Ave, 6507 WIMR2, Madison, WI, 53705, USA.
Sunil A; Division of Hematology, Medical Oncology, and Palliative Care, Department of Medicine, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Ave, 6507 WIMR2, Madison, WI, 53705, USA.
DeZeeuw AK; Division of Hematology, Medical Oncology, and Palliative Care, Department of Medicine, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Ave, 6507 WIMR2, Madison, WI, 53705, USA.
Gillette AA; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Sha GC; Division of Hematology, Medical Oncology, and Palliative Care, Department of Medicine, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Ave, 6507 WIMR2, Madison, WI, 53705, USA.
Johnson KA; Division of Hematology, Medical Oncology, and Palliative Care, Department of Medicine, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Ave, 6507 WIMR2, Madison, WI, 53705, USA.
Pasch CA; University of Wisconsin Carbone Cancer Center, Madison, WI, USA.
Clipson L; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, Madison, WI, USA.
Skala MC; University of Wisconsin Carbone Cancer Center, Madison, WI, USA.; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.; Morgridge Institute for Research, Madison, WI, USA.
Deming DA; Division of Hematology, Medical Oncology, and Palliative Care, Department of Medicine, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Ave, 6507 WIMR2, Madison, WI, 53705, USA. ddeming@medicine.wisc.edu.; University of Wisconsin Carbone Cancer Center, Madison, WI, USA. ddeming@medicine.wisc.edu.; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, Madison, WI, USA. ddeming@medicine.wisc.edu.
DB Label: Database : MEDLINE

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Human Colon Organoids and Other Laboratory Strategies to Enhance Patient Treatment Selection.

학술저널

issue: Current treatment options in oncology [Curr Treat Options Oncol] 2020 Apr 23; Vol. 21 (5), pp. 35. Date of Electronic Publication: 2020 Apr 23.
Author: Johnson KA; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
DeStefanis RA; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Emmerich PB; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Grogan PT; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Kratz JD; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Makkar SK; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Clipson L; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Deming DA; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA. ddeming@medicine.wisc.edu.; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA. ddeming@medicine.wisc.edu.
DB Label: Database : MEDLINE

원문보기: 등재 - Web of Science (SCIE) 등재 - SCOPUS 조회 - Impact Factor (JCR)

Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation.

학술저널

issue: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2019 Sep 01; Vol. 25 (17), pp. 5376-5387. Date of Electronic Publication: 2019 Jun 07.
Author: Pasch CA; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
Favreau PF; Morgridge Institute for Research, Madison, Wisconsin.
Yueh AE; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Babiarz CP; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Gillette AA; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin.
Sharick JT; Morgridge Institute for Research, Madison, Wisconsin.
Karim MR; Morgridge Institute for Research, Madison, Wisconsin.
Nickel KP; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin.
DeZeeuw AK; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Sprackling CM; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
Emmerich PB; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
DeStefanis RA; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Pitera RT; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Payne SN; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
Korkos DP; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Clipson L; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, Madison, Wisconsin.
Walsh CM; Morgridge Institute for Research, Madison, Wisconsin.
Miller D; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Carchman EH; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.; Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin.
Burkard ME; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Lemmon KK; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
Matkowskyj KA; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin.; William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin.
Newton MA; Departments of Statistics and of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin.
Ong IM; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.; Departments of Statistics and of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin.
Bassetti MF; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin.
Kimple RJ; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin.
Skala MC; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.; Morgridge Institute for Research, Madison, Wisconsin.; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin.
Deming DA; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin. ddeming@medicine.wisc.edu.; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, Madison, Wisconsin.
DB Label: Database : MEDLINE

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Tissue-Specific Oncogenic Activity of KRAS A146T .

학술저널

issue: Cancer discovery [Cancer Discov] 2019 Jun; Vol. 9 (6), pp. 738-755. Date of Electronic Publication: 2019 Apr 05.
Author: Poulin EJ; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Bera AK; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Lu J; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Lin YJ; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Strasser SD; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Paulo JA; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts.
Huang TQ; Department of Pediatrics and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.
Morales C; Department of Pediatrics and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.
Yan W; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Cook J; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Nowak JA; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.
Brubaker DK; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Joughin BA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Johnson CW; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
DeStefanis RA; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Ghazi PC; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Gondi S; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Wales TE; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts.
Iacob RE; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts.
Bogdanova L; Department of Pediatrics and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.
Gierut JJ; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Li Y; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Engen JR; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts.
Perez-Mancera PA; Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Braun BS; Department of Pediatrics and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.
Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts.
Lauffenburger DA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Westover KD; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas. khaigis@bidmc.harvard.edu Kenneth.Westover@UTSouthwestern.edu.
Haigis KM; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts. khaigis@bidmc.harvard.edu Kenneth.Westover@UTSouthwestern.edu.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Harvard Digestive Disease Center, Harvard Medical School, Boston, Massachusetts.
DB Label: Database : MEDLINE

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Targeted Therapy in Metastatic Colorectal Cancer: Current Standards and Novel Agents in Review.

학술저널

issue: Current colorectal cancer reports [Curr Colorectal Cancer Rep] 2019 Apr; Vol. 15 (2), pp. 61-69. Date of Electronic Publication: 2019 Mar 20.
Author: DeStefanis RA; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison.
Kratz JD; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison.
Emmerich PB; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison.
Deming DA; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison.; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison.; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison.
DB Label: Database : MEDLINE

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MTORC1/2 Inhibition as a Therapeutic Strategy for PIK3CA Mutant Cancers.

학술저널

issue: Molecular cancer therapeutics [Mol Cancer Ther] 2019 Feb; Vol. 18 (2), pp. 346-355. Date of Electronic Publication: 2018 Nov 13.
Author: Fricke SL; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Payne SN; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.
Favreau PF; Morgridge Institute for Research, Madison, Wisconsin.
Kratz JD; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Pasch CA; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.
Foley TM; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Yueh AE; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Van De Hey DR; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Depke MG; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Korkos DP; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Sha GC; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
DeStefanis RA; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Clipson L; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, Madison, Wisconsin.
Burkard ME; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.
Lemmon KK; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.
Parsons BM; Gundersen Health System, La Crosse, Wisconsin.
Kenny PA; Gundersen Health System, La Crosse, Wisconsin.
Matkowskyj KA; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin.; William S Middleton Memorial Veterans Hospital, Madison, Wisconsin.
Newton MA; Department of Statistics and Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin.
Skala MC; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.; Morgridge Institute for Research, Madison, Wisconsin.; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin.
Deming DA; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin. ddeming@medicine.wisc.edu.; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, Madison, Wisconsin.
DB Label: Database : MEDLINE

원문보기: Full Text (AACR) 등재 - Web of Science (SCIE) 조회 - Impact Factor (JCR)

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