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3
Direct formation of contrathermodynamic spiroketals: Synthetic studies toward the CD-subunit (C17-C28) of spongistatin 1 (altohyrtin A) 미리보기

학술저널

issue
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY; SEP 2003, 226 pU163-pU163, 1p.
Author
Rychnovsky, SD
Takaoka, LR
Buckmelter, AJ
DB Label
Database : Science Citation Index Expanded
원문보기
등재 - Web of Science 
4
Synthesis, equilibration, and coupling of 4-lithio-1,3-dioxanes: Synthons for syn- and anti-1,3-diols 미리보기

학술저널

issue
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY; APR 2 1998, 215 pU106-pU106, 1p.
Author
Buckmelter, AJ
Rychnovsky, SD
Dahanukar, VH
Skalitzky, DJ
DB Label
Database : Science Citation Index Expanded
원문보기
등재 - Web of Science 
5
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation. 미리보기

학술저널

issue
Life science alliance [Life Sci Alliance] 2020 Jul 07; Vol. 3 (8). Date of Electronic Publication: 2020 Jul 07 (Print Publication: 2020).
Author
Rusilowicz-Jones EV; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Jardine J; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Kallinos A; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Pinto-Fernandez A; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Guenther F; Alzheimer's Research UK, Oxford Drug Discovery Institute, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Giurrandino M; Alzheimer's Research UK, Oxford Drug Discovery Institute, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Barone FG; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
McCarron K; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Burke CJ; FORMA Therapeutics, Watertown, MA, USA.
Murad A; FORMA Therapeutics, Watertown, MA, USA.
Martinez A; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Marcassa E; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Gersch M; Chemical Genomics Centre, Max-Planck-Institute of Molecular Physiology, Dortmund, Germany.; Department of Chemistry and Chemical Biology, Technische Universität Dortmund, Dortmund, Germany.
Buckmelter AJ; FORMA Therapeutics, Watertown, MA, USA.
Kayser-Bricker KJ; FORMA Therapeutics, Watertown, MA, USA.
Lamoliatte F; Laboratory for Biological Mass Spectrometry, Newcastle University Biosciences Institute, Faculty of Medical Sciences, University of Newcastle, Newcastle, UK.
Gajbhiye A; Laboratory for Biological Mass Spectrometry, Newcastle University Biosciences Institute, Faculty of Medical Sciences, University of Newcastle, Newcastle, UK.
Davis S; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Scott HC; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Murphy E; Alzheimer's Research UK, Oxford Drug Discovery Institute, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
England K; Alzheimer's Research UK, Oxford Drug Discovery Institute, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Mortiboys H; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK.
Komander D; Ubiquitin Signalling Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.
Trost M; Laboratory for Biological Mass Spectrometry, Newcastle University Biosciences Institute, Faculty of Medical Sciences, University of Newcastle, Newcastle, UK.
Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Ioannidis S; FORMA Therapeutics, Watertown, MA, USA.
Ahlijanian MK; FORMA Therapeutics, Watertown, MA, USA.
Urbé S; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK urbe@liv.ac.uk.
Clague MJ; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK clague@liv.ac.uk.
DB Label
Database : MEDLINE
원문보기
Open Access (PubMed Central)  등재 - Web of Science (SCIE)  등재 - SCOPUS  조회 - Impact Factor (JCR) 
6
Molecular basis of USP7 inhibition by selective small-molecule inhibitors. 미리보기

학술저널

issue
Nature [Nature] 2017 Oct 26; Vol. 550 (7677), pp. 481-486. Date of Electronic Publication: 2017 Oct 18.
Author
Turnbull AP; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK.
Ioannidis S; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Krajewski WW; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK.
Pinto-Fernandez A; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK.
Heride C; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.
Martin ACL; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK.
Tonkin LM; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK.
Townsend EC; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Buker SM; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Lancia DR; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Caravella JA; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Toms AV; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Charlton TM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK.
Lahdenranta J; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Wilker E; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Follows BC; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Evans NJ; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK.
Stead L; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.
Alli C; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK.
Zarayskiy VV; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Talbot AC; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Buckmelter AJ; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Wang M; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
McKinnon CL; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Saab F; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK.
McGouran JF; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK.
Century H; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK.
Gersch M; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Pittman MS; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK.
Marshall CG; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Raynham TM; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK.
Simcox M; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Stewart LMD; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK.
McLoughlin SB; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK.
Escobedo JA; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Bair KW; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Dinsmore CJ; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Hammonds TR; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK.
Kim S; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA.
Urbé S; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.
Clague MJ; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.
Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK.
Komander D; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
DB Label
Database : MEDLINE
원문보기
Full Text (Nature)  등재 - Web of Science (SCIE)  등재 - SCOPUS  조회 - Impact Factor (JCR) 
7
Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility. 미리보기

학술저널

issue
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2015 Feb 01; Vol. 25 (3), pp. 529-41. Date of Electronic Publication: 2014 Dec 17.
Author
Zak M; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: mzak@gene.com.
Liederer BM; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Sampath D; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Yuen PW; Pharmaron Beijing Co. Ltd, 6 Taihe Road, BDA, Beijing 100176, PR China.
Bair KW; Forma Therapeutics Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Baumeister T; Forma Therapeutics Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Buckmelter AJ; Forma Therapeutics Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Clodfelter KH; Forma Therapeutics Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Cheng E; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Crocker L; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Fu B; Pharmaron Beijing Co. Ltd, 6 Taihe Road, BDA, Beijing 100176, PR China.
Han B; Forma Therapeutics Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Li G; Pharmaron Beijing Co. Ltd, 6 Taihe Road, BDA, Beijing 100176, PR China.
Ho YC; Forma Therapeutics Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Lin J; Forma Therapeutics Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Liu X; Pharmaron Beijing Co. Ltd, 6 Taihe Road, BDA, Beijing 100176, PR China.
Ly J; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
O'Brien T; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Reynolds DJ; Forma Therapeutics Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Skelton N; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Smith CC; Forma Therapeutics Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Tay S; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Wang W; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Wang Z; Forma Therapeutics Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Xiao Y; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Zhang L; Pharmaron Beijing Co. Ltd, 6 Taihe Road, BDA, Beijing 100176, PR China.
Zhao G; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Zheng X; Forma Therapeutics Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Dragovich PS; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
DB Label
Database : MEDLINE
원문보기
Full Text (ScienceDirect)  등재 - Web of Science (SCIE)  등재 - SCOPUS  조회 - Impact Factor (JCR) 
8
Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors. 미리보기

학술저널

issue
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2014 Jan 01; Vol. 24 (1), pp. 337-43. Date of Electronic Publication: 2013 Nov 14.
Author
Zheng X; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA. Electronic address: xzheng@formatherapeutics.com.
Baumeister T; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Buckmelter AJ; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Caligiuri M; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Clodfelter KH; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Han B; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Ho YC; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Kley N; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Lin J; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Reynolds DJ; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Sharma G; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Smith CC; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Wang Z; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
Dragovich PS; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Oh A; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Wang W; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Zak M; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Wang Y; Pharmaron Beijing, Co. Ltd, 6 Tai He Road, BDA, Beijing 100176, PR China.
Yuen PW; Pharmaron Beijing, Co. Ltd, 6 Tai He Road, BDA, Beijing 100176, PR China.
Bair KW; Forma Therapeutics, Inc., 500 Arsenal Street, Watertown, MA 02472, USA.
DB Label
Database : MEDLINE
원문보기
Full Text (ScienceDirect)  등재 - Web of Science (SCIE)  등재 - SCOPUS  조회 - Impact Factor (JCR) 
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