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Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.

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issue: Lancet (London, England) [Lancet] 2021 Mar 06; Vol. 397 (10277), pp. 881-891. Date of Electronic Publication: 2021 Feb 19.
Author: Voysey M; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Costa Clemens SA; Institute of Global Health, University of Siena, Siena, Italy; Department of Paediatrics, University of Oxford, Oxford, UK.
Madhi SA; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Innovation/National Research Foundation South African Research Chair Initiative in Vaccine Preventable Diseases Unit, University of the Witwatersrand, Johannesburg, South Africa.
Weckx LY; Department of Pediatrics, Universidade Federal de São Paulo, São Paulo, Brazil.
Folegatti PM; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Aley PK; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Angus B; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Baillie VL; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Innovation/National Research Foundation South African Research Chair Initiative in Vaccine Preventable Diseases Unit, University of the Witwatersrand, Johannesburg, South Africa.
Barnabas SL; Family Centre for Research with Ubuntu, Department of Paediatrics, University of Stellenbosch, Cape Town, South Africa.
Bhorat QE; Soweto Clinical Trials Centre, Soweto, South Africa.
Bibi S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Briner C; Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Cicconi P; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Clutterbuck EA; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Collins AM; Department of Clinical Sciences, Liverpool School of Tropical Medicine and Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Cutland CL; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Innovation/National Research Foundation South African Research Chair Initiative in Vaccine Preventable Diseases Unit, University of the Witwatersrand, Johannesburg, South Africa.
Darton TC; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK; Department of Infection and Tropical Medicine, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Dheda K; Division of Pulmonology, Groote Schuur Hospital and the University of Cape Town, Cape Town, South Africa; Faculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene & Tropical Medicine, London, UK.
Dold C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Duncan CJA; Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK; Translational and Clinical Research Institute, Immunity and Inflammation Theme, Newcastle University, Newcastle upon Tyne, UK.
Emary KRW; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Ewer KJ; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Flaxman A; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Fairlie L; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Faust SN; NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, University of Southampton, Southampton, UK; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK.
Feng S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Ferreira DM; Department of Clinical Sciences, Liverpool School of Tropical Medicine and Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Finn A; School of Population Health Sciences, University of Bristol and University Hospitals Bristol and Weston NHS Foundation Trust, UK.
Galiza E; St George's Vaccine Institute, St George's, University of London, London, UK.
Goodman AL; Department of Infection, Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, London, UK; MRC Clinical Trials Unit, University College London, London, UK.
Green CM; Clinical BioManufacturing Facility, University of Oxford, Oxford, UK.
Green CA; NIHR/Wellcome Trust Clinical Research Facility, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Greenland M; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Hill C; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Innovation/National Research Foundation South African Research Chair Initiative in Vaccine Preventable Diseases Unit, University of the Witwatersrand, Johannesburg, South Africa.
Hill HC; Department of Clinical Sciences, Liverpool School of Tropical Medicine and Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Hirsch I; AstraZeneca BioPharmaceuticals, Cambridge, UK.
Izu A; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Innovation/National Research Foundation South African Research Chair Initiative in Vaccine Preventable Diseases Unit, University of the Witwatersrand, Johannesburg, South Africa.
Jenkin D; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Joe CCD; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Kerridge S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Koen A; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Innovation/National Research Foundation South African Research Chair Initiative in Vaccine Preventable Diseases Unit, University of the Witwatersrand, Johannesburg, South Africa.
Kwatra G; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Innovation/National Research Foundation South African Research Chair Initiative in Vaccine Preventable Diseases Unit, University of the Witwatersrand, Johannesburg, South Africa.
Lazarus R; Severn Pathology, North Bristol NHS Trust, Bristol, UK.
Libri V; NIHR UCLH Clinical Research Facility and NIHR UCLH Biomedical Research Centre, London, UK.
Lillie PJ; Department of Infection, Hull University Teaching Hospitals NHS Trust, Hull, UK.
Marchevsky NG; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Marshall RP; AstraZeneca BioPharmaceuticals, Cambridge, UK.
Mendes AVA; Escola Bahiana de Medicina e Saúde Pública, Salvador, Braziland Hospital São Rafael, Salvador, Brazil; Instituto D'Or, Salvador, Brazil.
Milan EP; Universidade Federal do Rio Grande do Norte, Natal, Brazil.
Minassian AM; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
McGregor A; London Northwest University Healthcare, Harrow, UK.
Mujadidi YF; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Nana A; Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Padayachee SD; Setshaba Research Centre, Pretoria, South Africa.
Phillips DJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Pittella A; Hospital Quinta D'Or, Rede D'Or, Rio De Janeiro, Brazil.
Plested E; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Pollock KM; NIHR Imperial Clinical Research Facility and NIHR Imperial Biomedical Research Centre, London, UK.
Ramasamy MN; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Ritchie AJ; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Robinson H; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Schwarzbold AV; Clinical Research Unit, Department of Clinical Medicine, Universidade Federal de Santa Maria, Santa Maria, Brazil.
Smith A; College of Medical, Veterinary & Life Sciences, Glasgow Dental Hospital & School, University of Glasgow, Glasgow, UK.
Song R; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Snape MD; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Sprinz E; Infectious Diseases Service, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Sutherland RK; Clinical Infection Research Group, Regional Infectious Diseases Unit, Western General Hospital, Edinburgh, UK.
Thomson EC; MRC-University of Glasgow Centre for Virus Research & Department of Infectious Diseases, Queen Elizabeth University Hospital, Glasgow, UK.
Török ME; Department of Medicine, University of Cambridge, UK; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Toshner M; Heart Lung Research Institute, Dept of Medicine, University of Cambridge and NIHR Cambridge Clinical Research Facility, Cambridge University Hospital and Royal Papworth NHS Foundation Trusts, Cambridge, UK.
Turner DPJ; University of Nottingham and Nottingham University Hospitals NHS Trust, Nottingham, UK.
Vekemans J; AstraZeneca BioPharmaceuticals, Cambridge, UK.
Villafana TL; AstraZeneca BioPharmaceuticals, Cambridge, UK.
White T; AstraZeneca BioPharmaceuticals, Cambridge, UK.
Williams CJ; Public Health Wales, Cardiff, Wales; Aneurin Bevan University Health Board, Newport, Wales.
Douglas AD; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Hill AVS; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Lambe T; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Gilbert SC; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK. Electronic address: andrew.pollard@paediatrics.ox.ac.uk.
DB Label: Database : MEDLINE

원문보기: Full Text (ScienceDirect) Full Text (Clinical Key) 조회 - Impact Factor (JCR) 등재 - Web of Science (SCIE) 등재 - SCOPUS

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