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Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.

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issue: Nature [Nature] 2023 Apr; Vol. 616 (7957), pp. 553-562. Date of Electronic Publication: 2023 Apr 13.
Author: Abbosh C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. c.abbosh@ucl.ac.uk.
Frankell AM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Harrison T; Invitae, San Francisco, CA, USA.
Kisistok J; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.
Garnett A; Invitae, San Francisco, CA, USA.
Johnson L; Invitae, San Francisco, CA, USA.
Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Moreau M; Invitae, San Francisco, CA, USA.
Chesh A; Invitae, San Francisco, CA, USA.
Chaunzwa TL; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Weiss J; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Department of Radiology, Freiburg University Hospital, Freiburg, Germany.
Schroeder MR; Invitae, San Francisco, CA, USA.
Ward S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.
Grigoriadis K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Shahpurwalla A; Invitae, San Francisco, CA, USA.
Litchfield K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Tumour Immunogenomics and Immunosurveillance Laboratory, University College London Cancer Institute, London, UK.
Puttick C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Biswas D; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK.
Karasaki T; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.
Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Bakir MA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Lim EL; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Huebner A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Moore DA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.
Godin-Heymann N; AstraZeneca, Cambridge, UK.
L'Hernault A; AstraZeneca, Cambridge, UK.
Bye H; AstraZeneca, Cambridge, UK.
Odell A; Invitae, San Francisco, CA, USA.
Roberts P; Invitae, San Francisco, CA, USA.
Gomes F; The Christie NHS Foundation Trust, Manchester, UK.
Patel AJ; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.
Manzano E; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Hiley CT; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Carey N; Cancer Research Centre, University of Leicester, Leicester, UK.
Riley J; Cancer Research Centre, University of Leicester, Leicester, UK.
Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.
Hodgson D; AstraZeneca, Cambridge, UK.
Stetson D; AstraZeneca, Waltham, MA, USA.
Barrett JC; AstraZeneca, Waltham, MA, USA.
Kortlever RM; Department of Biochemistry, University of Cambridge, Cambridge, UK.
Evan GI; Department of Biochemistry, University of Cambridge, Cambridge, UK.
Hackshaw A; Cancer Research UK & UCL Cancer Trials Centre, London, UK.
Daber RD; Invitae, San Francisco, CA, USA.
Shaw JA; Cancer Research Centre, University of Leicester, Leicester, UK.
Aerts HJWL; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Radiology and Nuclear Medicine, CARIM & GROW, Maastricht University, Maastricht, The Netherlands.
Licon A; Invitae, San Francisco, CA, USA.
Stahl J; Invitae, San Francisco, CA, USA.
Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.
Birkbak NJ; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.
McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.
Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. Charles.Swanton@crick.ac.uk.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. Charles.Swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. Charles.Swanton@crick.ac.uk.
DB Label: Database : MEDLINE

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